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Patient education is also a recognised factor in achieving a high level of persistence; the French guidelines reinforce this by recommending patients have a consultation dedicated to providing disease and treatment information prior to commencing drug treatment [ 9].
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These clinical data suggest that obesity/diabetes are risk factors for hepatic fibrosis and progression to cirrhosis, a recognised predisposing factor for HCC regardless of the underlying cause of hepatic cirrhosis (Zaman et al, 1985).
The pretreatment CA 15.3 level is a recognised prognostic factor, but it has not been proven to be an independent prognostic factor (standard, level of evidence: B2).
Lidgren et al. [34] reported age at the time of surgery to be a recognised risk factor for implant survival both in UKR and TKR.
Obesity is a recognised risk factor for poor bowel preparation in retrospective studies whilst corresponding data in prospective trials are marginally reported.
Although sharing needles/syringes (N/S) is a recognised risk factor for the hepatitis C virus (HCV), epidemiological studies have shown inconsistent associations between self-reported N/S sharing and biological markers of HCV infection.
Cancer, particularly when metastatic (spread to other places in the body), is a recognised risk factor for thrombosis.
Ionising radiation is a recognised risk factor [ 47].
Cancer is a recognised risk factor for VTE.
Asian ethnicity is a recognised risk factor for OASI [ 8].
The rarity of such databases is a recognised limiting factor.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com