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A recent trial evaluating thermostatic control of social housing estate boiler houses with daily sterilisation demonstrated significant reductions in hot tap water temperature [67].
In a recent trial evaluating ECMO for OHCA, initiation of ECMO required two critical care physicians for cannulation, a third physician providing ultrasound guidance of cannula placement in the inferior vena cava, a fourth physician dedicated to leading the resuscitation, a nurse coordinator to initiate the circuit, and a sixth person to infuse cold saline for intra-arrest hypothermia [ 15].
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The most recent trial evaluating panitumumab in BTC used the chemotherapeutic backbone of gemcitabine and irinotecan resulting in a response rate of 31% with median PFS 9.7 months and OS 12.9 months (Sohal et al, 2013).
29 In their more recent trial evaluating hypnotherapy for hot flashes in postmenopausal women, Elkins et al 28 used a structured-attention control designed to mimic the hypnotherapy intervention without therapeutic intent.
Another recent trial evaluating motivational interviewing among MSM club drug users found significant reductions in self-reported club drug use in the intervention arm compared with the control arm but only among the subset of non-severely dependent participants.
The largest of the recent trials evaluating XELOX, NO16966 (XELOX-1), started as a two-arm, randomised, non-inferiority, phase III study designed to compare XELOX with FOLFOX4 as first-line treatment for metastatic colorectal cancer.
We look at two recent trials evaluating their impact on mortality.
Two recent trials evaluating novel therapies for patients with multiple myeloma, for example, assessed HRQoL using EORTC QLQ-C30 with or without its myeloma-specific module EORTC QLQ-MY20, yet neither trial collected EQ-5D data [ 6, 7].
Two more recent trials evaluated a combination of artesunate and praziquantel compared to praziquantel alone.
In a recent clinical trial evaluating the efficacy of green tea extract (GTE) on prostate cancer, it was found that the GTE had minimal clinical activity [ 7, 8].
Furthermore, a recent randomized trial evaluating intra- and postoperative goal-directed fluid therapy (GDT) concluded that avoiding hypovolaemia by GDT was not sufficient to decrease the occurrence of OI during mobilization after prostatectomy [ 8].
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