The aim of the modelling presented here was to determine the costs and effectiveness for hospital and community-based systems of Neonatal hearing screening in England and Wales with a special regard to the effects of reasonable alterations to parameter values.
What if the land could be made habitable with reasonable alterations, she wondered.
Sensitivity analyses showed that the model results were robust to reasonable alterations in inputs and assumptions; ICERs were particularly sensitive to changes in the number of ranibizumab injections and the time horizon of the model.
Enlightened by the conformational alteration, a reasonable explanation for the increased OPH activity was proposed: I211A substitution decreases the size of the side chain, which offers enough space for the motion of the flexible loop10, and the conformational migration in loop10 makes the side chain of His157 move closer to the methoxyl group of MP, generating a much stronger interaction with MP.
The goal of the proposed quality metric is to detect, with a reasonable accuracy, three synthetic alterations which may deeply affect the most widely used matching systems.
It detects with a reasonable accuracy three types of alterations that may deeply affect the global performance of the most widely used matching systems.
Keep in mind that if it doesn't feel right or look good when you try it on, then it probably isn't the piece for you (subject to a reasonable assessment of the potential for alterations).
This seems a reasonable choice, since it can be argued that alterations induced in this system as a result of a toxic insult could lead to impaired immunity.
If R210K causes only a subtle localized alteration in active site conformation, the barrier lowering pathway is a reasonable explanation for its near wild-type function.
Hydrothermal alteration, which causes the breakdown of feldspar and the new formation of white mica, is a reasonable mechanism to explain the increase in the amount of illite in the fault core at around 41.34 mbgs.
The alterations seemed to give Arsenal the freshness they needed and their 4-3-3 formation posed a reasonable attacking threat.
