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The phrase "a realistic breakthrough" is correct and usable in written English.
It can be used when discussing an achievement or advancement that is practical and achievable, often in a scientific or technological context.
Example: "The researchers announced a realistic breakthrough in renewable energy technology that could significantly reduce carbon emissions."
Alternatives: "a practical advancement" or "a feasible innovation."
Exact(1)
At the same time, a realistic breakthrough was achieved by Laura Fitinghoff, whose historical novel about the famine of the 1860s, Barnen från Frostmofjället (1907; Eng. trans., Children of the Moor, 1927), ranks as a classic.
Similar(59)
A realistic invisible man.
A breakthrough in battery chemistry or another technology, such a regenerative braking, will be needed to bring costs down enough to make electric cars a realistic mass-market prospect.
There are important incremental advances in robots virtually every day, and occasionally major breakthroughs, like the Microsoft Kinect 3-D sensor that makes affordable indoor 3-D vision for video games a realistic target.
It is a realistic ambition.
You're a realistic optimist.
Developing a Realistic Schedule.
In the discussion, the California entrepreneur says key technology breakthroughs are dramatically lowering the cost of space access to the point where a mission to the Red Planet will very soon become a realistic financial prospect.
It's a realistic goal".
Scientists are a realistic bunch.
A Realistic Solution.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com