Sentence examples for a rationale for engineering from inspiring English sources
The integration of HA with integrin-specific ECM signaling proteins provides a rationale for engineering a new class of soft hybrid hydrogels that can be used in therapeutic strategies to reverse the remodeling of the injured myocardium.
This provides a strong rationale for engineering the Fc domain of trastuzumab to better interact with low-binding alleles of activating FcγRs to expand, without regard to FcγR genotype, the benefit of treatment to patients.
This study (1) uncovers the structural determinants of FMDV thermolability, (2) investigates the relationship between virus thermolability and infectivity, and (3) provides a structure-based rationale for engineering thermostable virus particles to develop improved vaccines and nanocontainers.
While the field has generally moved away from linkers that provide slow nonspecific cleavage of the ADC (such as the hydrazone linker used to prepare Mylotarg) due to concerns about toxicity arising from premature drug release, the rationale for engineering a half-life into the linker here was to use it with antibodies targeting poorly internalized antigens.
In addition, the biological rationale for engineering DDC, a small non-peptide molecule with a molecular weight of 700 Da (as compared with the 36-kDa annexin V protein), is that such small molecules could benefit from less immunogenicity and the favorable biodistribution kinetics that small compounds in general exhibit over bigger proteins.
In this chapter, we describe the rationale for engineering stable immunoliposome-based therapeutics, methods required for preparation of immunoliposomes, as well as for their physicochemical and in vivo characterization.
In this review, we discuss the rationale for engineering tissues and organs by combining computer-aided design with additive manufacturing technologies that encompass the simultaneous deposition of cells and materials.
But you still have to offer a rationale for the purchase, such as the car's engineering or whatever.
Not exactly a rationale for an apology.
No one has a rationale for this".
Kennedy had yet to establish a rationale for his candidacy.
