geNorm produced a consistent gene ranking across all of our samples, and provides a clear rationale for determining the minimum number of genes required for accurate normalization.
The main aim of job evaluation is to provide an acceptable rationale for determining the pay of existing hierarchies of jobs and for slotting in new ones.
The rationale for determining the stress intensity factors under mixed-mode loading conditions and the calibration curves, relevant to a number of orthotropic materials, relating maximum load and loading angle to KI and KII are presented.
Results from this study provided rationale for determining end-points of interest in stage 1 hypertensive men 10 hours after ingesting Q or P. In stage 1 hypertensive individuals, plasma Q increased 0.6 ± 0.4 vs. 0.05 ± 0.02 μmol/L), and mean BP decreased (103 ± 7 vs 108 ± 7 mm Hg; both P <.05) 10 hours after Q vs P, respectively.
The rationale for determining the contribution of every pixels fluorescence intensity to the r×R map instead of using any of the coefficients by itself is as follows: the individual contribution of every pixel to the r can be negative or positive (Table 1, Fig. S2), which in general we attribute to colocalized and anti-colocalized pixels.
These studies highlighted the rationale for determining if the T3SS of C. psittaci was able to modulate the host inflammatory response.
Whether the overall aim of setting a cutoff point for insulin resistance is to guide treatment in patients with type 2 diabetes or to prevent or delay the development of diabetes in the general population, the rationale for determining insulin resistance should be clearly defined in order for the cutoff point to be useful.
Computational models will need to be developed to determine how polygenes and environmental factors interact to perturb cellular regulatory networks, affecting cellular phenotypes and determining a rationale for targeted prevention of disease (Schadt et al. 2009).
The results of AVOID-HF nevertheless provide a rationale for well-designed, adequately powered trials to determine whether ultrafiltration has a role in the routine management of acute decompensated heart failure.
We expect that the results of these trials will provide a rationale for a larger randomized clinical trial to determine the efficacy of the GPC3-derived peptide vaccine and to advance future drug development.
