Exact(11)
But the very process of imposing a rational structure gives government extraordinary power.
In this Article we argue that there is a rational structure to the doctrine of corporate veil piercing not only in theory, but in practice as well.
The mind is fundamentally a rational structure, and rational connections are a priori, rather than having to be discovered empirically, as causal connections are.
The city's Department of Transportation says the new design imposes a rational structure on the flow of traffic and calms everything down.
This formal order becomes a rational structure that gives to the work its mix of frigidity and heat, a perfectly ambiguous cocktail for an ambiguous moment and an antidote to the weary sophistication of which there is too much in art now (Kimmelman).
This formal order becomes a rational structure that gives the work its mix of frigidity and heat, a perfectly ambiguous cocktail for an ambiguous moment and an antidote to the weary sophistication of which there is too much in art now (Kimmelman).
Similar(48)
Ultimately, a rational structure-based design strategy was successful for the identification of Siah inhibitors in which peptide binding drives specific covalent bond formation with the target.
In this work, we report a rational structure-based approach aimed at the discovery of new 2-aminoimidazoles as β-secretase inhibitors.
Altogether, our findings show how a rational structure-based drug design approach coupled to cell-based drug evaluation strategies can be applied in medicinal chemistry to identify new agents targeting a given oncogenic-dependency setting.
Based on the enzyme-product complex, this paper goes on to describe a rational, structure-based redesign of the enzyme, which offers the opportunity to produce novel strictosidine derivatives which can be used to generate alkaloid libraries of the N-analogues heteroyohimbine type.
The studies reported in this work were undertaken to establish whether the NQR method could be used to derive a rational structure-activity relationship for these inhibitors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com