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The models provide a rational explanation why oxidation of methionine residues completely abolishes ccβ-Met amyloid fibril formation, indicating that a small number of site-specific hydrophobic interactions can play a major role in the packing of polypeptide-chain segments within amyloid fibrils.
This observation underlines the mechanistic heterogeneity of multiple sclerosis and provides a rational explanation why some patients benefit from antibody depleting treatments.
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"I can't believe they can come up with a rational explanation of why this is a national security issue," said Michael W. Hunkapiller, the chief executive of Pacific Biosciences.
"I had to talk to four of my guys and somehow come up with a rational explanation of why they weren't going to play," Love said.
The objective then was to develop a rational explanation for why the polymer alternated, i.e. by addition of one molecule of carbon dioxide monomer was invariably followed by one molecule of cyclohexene epoxide, and then again by CO2.
Another is that we are left without a rational explanation of why a kimu would be eager to enter snorf-infested space when the snorf are near red, other than that they are psychologically incapable of correctly representing the presence of snorf when snorf are near red.
But the most important thing is to remind yourself that there is a rational explanation for why you feel the way you feel and that it's not irreparable.
The new rules require agencies to carefully consider and justify bundling of contracts and to provide a rational explanation detailing why the bundled contract cannot be split among multiple small businesses.
Marcus points out that there's always a rational explanation for why Obama is strangely inconspicuous during a given event but, as has been often observed, the apparent upshot is a man unwilling to articulate a moral stance, to stand for anything.
Our data, summarized in Figure 6, provide a rational explanation of why H5 HA has not yet adapted in this way.
This gives a rational explanation for why only some oats trigger an immunological response.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com