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His studies helped shift medical emphasis from mystical speculation to a rational application of universal laws of physics and chemistry.
Is it going to be a rational application of cores vs. just adding more and more cores, which was the prediction five years ago?
We found that the mutated p53 gene correlated with increased resistance to DNA-damaging agents but the sensitivity to anti-microtubule agents was independent of the mutation, suggesting a clinical significance of the status of p53 gene in astrocytic tumours and a rational application of anti-microtubule agents to the patients with p53-mutated astrocytic tumours.
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As several different regimens are being used, a better understanding of the individual tumour microenvironment might enable a more rational application of these therapies along with the incorporation of hypoxia-modifying treatments for those patients with hypoxic tumours.
The OrBiTo project will address key gaps in our knowledge of gastrointestinal (GI) drug absorption and deliver a framework for rational application of predictive biopharmaceutics tools for oral drug delivery.
However, a critical review of indications and added value of these techniques are a prerequisite for rational application and maximum diagnostic yield.
In all, our study on dose-effect relationship of CDTHD provided a useful reference for the rational application of CDTHD in clinic and also supplied the research model of large dose application in TCM.
A significant hurdle to the rational application of miRNAs as therapeutics is our current inability to reliably predict the range of molecular and cellular consequences of perturbations in the levels of specific miRNAs on targeted cells.
The availability of robust methods to assess disease biology will further enable a personalised approach to therapy, allowing the rational application of both surgery and chemotherapy in an individual patient and minimising the exposure to morbid inventions.
The ability to identify periods with a higher number of malaria cases by using an early detection method will enable the more rational application of malaria control methods.
This work offers a basis for the optimized design, improved performance, and rational application of UAV.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com