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But today's Government is much more complex – it is about managing projects, solving problems rather than standing back in a rather refined way and dreaming up new policy initiatives".
Therefore, in terms of prediction, we have come down to a rather refined set of features that can be employed in order to estimate the relapse probability for a specific patient.
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I refer of course to William Wyler's Wuthering Heights starring Laurence Olivier and Merle Oberon as Heathcliff and Cathy, which opened in 1939, and Robert Stevenson's foggy, gothic Jane Eyre, which appeared after a lengthy period of gestation in 1943, with Joan Fontaine as a beautiful, rather refined Jane, and Orson Welles as a wild, charismatic Rochester.
In recent years, some of the directors working on modest budgets (in and out of Hollywood) have developed a chaste and rather refined new style — a style devoted to minute perceptions of character that lead to small revelations of how life works.
And the same contradictions apply to Burberry's appeal: the famous check that seems the essence of sophisticated Britishness to many foreign customers is also the favourite badge of a rather less refined breed of football supporter.
"To me, they aren't isolated and inconvenient but rather refined and gracious," she said.
Her accent had once been rather refined, but presumably the numbing of her own senses over many years had coarsened it.
Mouse Morris has few airs and graces, which belies his rather refined family background.
While substantial evidence has been accumulated via rather refined and theory-based methods for CDM in physical conditions, research on CDM in mental illness is still at an early stage.
RSpredict computes all normalized energies based on the refined alignment, and the program uses loop lengths from the refined alignment A rather than the original input alignment Ao.
He's an assassin of a rather special, not to say refined sort.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com