By utilising a recombinant variant of FPV which expresses the nominal antigen chicken ovalbumin (OVA), and assessing innate FPV- and OVA-specific adaptive immune responses, we show that recombinant FPV induces a rapid type I interferon (IFN) response, mediated primarily by plasmacytoid dendritic cells (pDCs).
Subsequent results indicated the crucial role of TLR recognition by DC in the creation of a rapid type 1 innate immunity to T. gondii and to prevent acute mortality [ 18].
The type I IFN production requires IFN regulatory factor (IRF 7 to be phosphorylated and translocated into the nucleus through rapid interaction with MyD88 and IRF7 [ 4]. pDCs are found to constitutively express high levels of IRF7 and the endogenous IRF7 facilitates a rapid type I IFN response that is independent of type I IFN receptor-mediated feedback signaling [ 3, 5, 6].
Due to high polymorphism and multiple genes per haplotype, it has been difficult to develop a rapid typing method for rhesus monkey MHC class I.
Because of high polymorphism and multiple genes per haplotype, it has been difficult to develop a rapid typing method for cynomolgus monkey MHC class II.
FLiP is a modified mixed-linker PCR, a rapid typing method based on the PCR amplification of RFLP fragments containing the 3′ end of IS 6110 and resolving the amplicons by polyacrylamide gel electrophoresis [ 17].
Introduction of small, affordable, and rapid benchtop whole-genome sequencers, such as the Illumina MiSeq (Illumina, San Diego, CA, USA) MiSeq and the Ion Torrent PGM Life Technologiess, Carlsbad, CA, USA), has made it possible for clinical and public health laboratories to contemplate adding genome sequencing as a rapid typing tool.
Hence, robust modelling statistics revealed a extreme ecological similarity between the phylogenetically unrelated Psammophis and Coluber, clearly indicating that their peculiar morphologies have evolved to prey a rapid moving type of diurnal prey (lizards) in a specific type of microhabitat (tall grass).
We present a new program analysis algorithm, Rapid Type Analysis, and show that it is fast both in theory and in practice, and significantly out-performs other "fast" algorithms for virtual function call resolution.
While in graduate school, Bacon developed Rapid Type Analysis (RTA), a core optimization algorithm for object-oriented language (OOL) compilers that is now used in two IBM products.
On dynamic post-contrast images, they show a rapid rise type curve with significant enhancement during the early phase due to the hypervascular nature of these tumours [30].
