Prosecutors in the case, who had sought about 70 days before a trial, said that a more rapid schedule was unheard-of in a complex corporate investigation that would rely on the testimony of dozens of witnesses.
Within 3 weeks (i.e. by day 21) antibody levels were higher in Group R and Group A than in Group M and Group C. Group R and Group C both had higher titres on days 42, 180 and 300, than Group A and Group M. The rapid schedule thus combines the advantages of fast protection and of high titres over the observation period of 300 days.
However, the rapid schedule elicits a less marked immune response than the conventional schedule after the second dose, and antibodies have been seen to decline more rapidly.
However, while the rapid schedule elicits an earlier response than the conventional schedule, the duration of this response is shorter.
The conventional primary vaccination schedule is the same as for FSME-Immun® (on day 0, after 1 3 mo and after 9 12 mo); a rapid vaccination schedule consists of 3 doses on days 0, 7 and 21, and a first booster after 12 18 mo.
It is highly selective, releasing just one or two books a month on a rapid turnaround schedule, and publishes only when books are ordered by readers, either through print on demand or ebooks, bypassing the traditional book trade.
A new version of Firefox used to be a big deal, but since Mozilla switched to a rapid release schedule, these updates are becoming pretty routine.
The aim of the design process was to produce a practical, low-cost, small satellite mission with mainly commercial off-the-shelf components and a rapid development schedule.
High starting doses of medication and a rapid titration schedule in more vulnerable patients with past psychiatric history and with more severe epilepsy with high seizure frequency were associated with greater risk.
