A number of nonpeptide compounds that selectively block the NK1 receptor have been identified, and a typical feature of the NK1 antagonists was that these abolished emesis from a wide range of profound emetic stimuli, including apomorphine, morphine, nicotine, copper sulphate, ipecacuanha, radiation, cyclophosphamide, cisplatin, and motion in the ferret and the dog (Watson et al, 1995).
This phrase, originally from Shakespeare, is one I've used a few times, usually with a heavy dose of irony and in a range of absurd to profound situations.
We can predict their function through homology to enzymes and proteins of known function; however, undoubtedly they will differ in their ability to catalyse reactions, and some may be more efficient at their task, which would be of profound interest to a range of researchers and companies in biotechnology.
This discussion is timely given the range of profound health-related concerns facing both public health ethics and human rights.
Considering the range of profound deficits noted across subjects, it was notable that four of the 55 (7%) subjects in the group were found to be normal at onset and all of these remained normal throughout the study.
An exhibition at the Corcoran Gallery of Art in Washington DC shows a range of photos - iconic and unknown, profound and not - all about war and its aftermath.
Besides technological innovation, it also had profound cultural implications; a range of social science consultants having pioneered community creation models.
Now, neuroscientists have shown that they can make this experience physical, creating a "body swapping" illusion that could have a profound effect on a range of therapeutic techniques.
Mathias Risse argues that we all, collectively, own the resources of the earth and this has profound implications for a range of global justice issues, including immigration.
