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Most likely this is because of the scarce availability of isolates able to infect the same host while displaying a range of pathogenicity.
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These elements are known to carry accessory genes responsible for a range of functions including pathogenicity (Chuzeville et al. 2012; Seth-Smith et al. 2012), symbiosis (Sullivan et al. 1995; Sullivan et al. 2002), antibiotic resistance (Michael et al. 2012; Rodríguez-Blanco et al. 2012), and xenobiotic catabolism (Gaillard et al. 2006; Shettigar et al. 2012).
Globally, increasing evidence shows that in M. tuberculosis, transmission varies from strain to strain and that different strains exhibit a range of geographical and host specificities, pathogenicity, and drug susceptibility.
Although several genetic lineages of virus are distinguished, there is no specific marker of higher pathogenicity and a range of genetic strains caused devastating outbreaks in the 2000s in Malaysia (35), China, and Taiwan (36).
To unravel this interplay, we performed a systematic characterization of the global host response at the transcript and protein levels in lungs of mice infected by a panel of viruses that vary in pathogenicity, using a range of inoculation dosages.
The patterns of pathogenicity likely to be found in plant pathogen associations are markedly affected by a range of life-history characters of the pathogen that can ultimately influence its transmission rate (Burdon 1987).
This pathogenicity scoring system employs a number of weighted criteria covering a range of molecular, functional, and genetic data, from which an overall pathogenicity score (out of a total of 20 points) can be obtained.
These proteins contribute to pathogenicity by binding to a range of host factors mediating adhesion, invasion and resistance to the complement response.
A given microorganism pathogenicity is expressed as a range of damage which is caused by the microorganism itself and by the immune system as a response to a pathogen.
This resource will enable researchers to compare antigenic variation within and across taxa with the goal of identifying common mechanisms of pathogenicity to assist in the fight against a range of devastating diseases.
We determined the levels of Pythium necessary to cause disease by performing pathogenicity experiments using two Pythium species, a range of Pythium densities, and two common tree species (Acer rubrum and Prunus serotina) from the study sites.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com