Here we describe a novel protocol for inducing and assessing a range of deviations in body states via bolus infusions of isoproterenol, a non-selective beta adrenergic agonist.
An important conclusion is in a typical situation of variabilities a range of deviations exists, say between 5% and 25%, where the GMO is still equivalent to the reference varieties, although it is very likely to find a significant difference with the conventional counterpart.
A range of standard deviation multiples was used, from 0.5 to 5.0 in steps of 0.5 (i.e. decreasing penalization with increasing threshold).
There was substantial intrasubject systematic variability in CBF of gray matter ROIs corresponding to a range of standard deviations = [39 168] (ml/(100 g min)).
The values were chosen to be representative of typical meta-analyses exhibiting a range of standard deviations, number of trials, number of participants per trial, effect sizes, and heterogeneity.
The NmF2 values predicted by the CCIR option show a smaller range of deviation than the NmF2 values predicted by the URSI option.
Under NBA, output declines due to the import competition and decreases in exports, showing a wide range of deviation across sectors.
Twenty four college-age males exerted their maximum torque in both concentric flexion and extension at 60, 120, and 180°/s of angular velocity through a ±60° range of deviation from wrist neutral.
Although both the URSI and CCIR options of the IRI model predict NmF2 close to the NmF2obs especially during daytime, the CCIR option produces a smaller range of deviation than the URSI option.
Our study shows that: (1) In general, both the URSI and CCIR options of the IRI model give foF2 close to the measured ones, but the CCIR option produces a smaller range of deviation than the URSI option.
