The Performance Pages readouts add a range of analog-style engine and transmission gauges.
We employed our high-throughput screen assay against 646,275 compounds to discover inhibitors of Lsp and synthesized a range of analogs to generate molecules with nanomolar half maximal inhibitory concentration values.
The antibacterial activity of a range of analogs, including 5 and 6, against Mycobacteriumosis was evaluated, and it was found that the uridine, the aminoribose, and the fatty acyl side chains are crucial for antibacterial activity.
To further investigate the structure activity relationships (SAR) of the quinazoline scaffold, we designed and synthesized a range of analogs bearing different 2-amino substitutions and evaluated their inhibition potencies against both GLP and G9a.
We previously developed syringolin A analog 2 as a potent proteasome inhibitor by the structure-based drug design of syringolin A. In this Letter, we synthesized a range of analogs of 2, having a different length of the lipophilic chain and substituted aryl group, and their cytotoxicity against human cancer cells was evaluated.
Since the Met mutation resulted in a greater velocity at 100 μM N6(Benzy ATP than wildtype ROCK2, we analyzed this protein over a concentration range of analog to estimate Km for N6(Benzyl ATP.
A piece could land in a range of executions including analog collage, digital illustration, abstract image, or a combination".
Straightforward synthetic steps, starting from amino acids, allow the facile construction of a wide range of analogs.
We have discussed a range of gastrin and CCK analogs for targeting CCK2R positive tumors in this review.
We have developed a range of techniques useful for constructing analog and digital circuits for operation in a liquid Helium environment (4.2 K), using commercially available low power components.
