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The phrase "a radically different environment" is correct and usable in written English.
You can use it to describe a situation or setting that is significantly unlike another, often in terms of culture, conditions, or context.
Example: "After moving from the city to the countryside, I found myself in a radically different environment that changed my perspective on life."
Alternatives: "a completely new setting" or "a vastly altered atmosphere".
Exact(12)
However, no fundamental differences were detectable that would indicate a radically different environment or nutrient availability for growth in enterocytes.
These are developments that portend a radically different environment for the nation's workers.
After a decade in which companies flourished seemingly without effort -- the longest period of uninterrupted economic growth on record -- many executives now face a radically different environment, according to management consultants and some of the executives themselves.
We moved on, to the western end of the bay, where a grassy expanse of wetland and a bottom of rich mud created a radically different environment and fishing experience.
In an era when many architecture stars earned healthy commissions designing high-rise condominiums or corporate headquarters, Mr. Woods conceived of a radically different environment, one intended for a world in conflict.
But for several days in mid-August, Mr. Franklin, 32, decamped to a radically different environment, the bucolic Sundance Resort near Park City, Utah, where he happily unplugged to attend a biannual conference sponsored by the Threshold Foundation for young adults from wealthy families.
Similar(48)
· They think they can't handle the work or the radically different environment.
These students started college in fall 2005 and graduated into a radically different economic environment in spring 2009.
Major flashpoints in our changing climate are gradually forcing political leaders to prepare their populations for a radically different global environment.
The real challenge for the NHS today is to adapt to a radically different operating environment, where health needs are often chronic and complex, financial resources are pegged at current levels and the wider world is changing fast.
If you add the rampant diet industry, a radically different food environment and health concerns to the reach of the media, then it's no wonder there is so much confusion and anxiety.
More suggestions(10)
a radically different atmosphere
a significantly different environment
a radically different situation
a totally different environment
a radically different framework
a substantially different environment
a fundamentally different environment
a radically different climate
a completely different environment
a radically different picture
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com