The phrase "a radical modification of" is correct and usable in written English.
It can be used when discussing significant changes or alterations to something, often in a technical, scientific, or creative context.
Example: "The researchers proposed a radical modification of the existing model to improve its accuracy."
Alternatives: "a substantial change to" or "a significant alteration of".
Stratificational grammar is perhaps best characterized as a radical modification of post-Bloomfieldian linguistics, but it has many features that link it with European structuralism.
Immediately, a prominent Venetian architect and historian named Antonio Foscari published the first of several articles in Il Gazzettino, proposing a radical modification of the project and creating considerable buzz.
At a national level, each country is now considering a radical modification of its current training and licensing, based on models originally developed for car driving (e.g., the GDE matrix [18]).
Tumor cells display a radical modification of cellular metabolism, with increased glycolysis and lipogenesis, to support rapid growth and proliferation.
The evolution of FDG uptake reflects the efficacy of the medical treatment, and its careful assessment can lead to better modulation of the drug dosage or prompt a radical modification of the therapeutic strategy.
Encouragingly, Our legal advisers report that even a relatively radical modification of the current terms would not require amendments to any existing documentation, which was intentionally left open to interpretation, and which few participants bother to read in the first place.
The impact of a false-positive imaging diagnosis is less pronounced as this will not result in radical modification of the treatment strategy.
The described phenomenon of phase transition on the grain boundaries decreases in case of radical modification of the existing process engineering of handling metals.
This indicates carbonyl group formation and thus evidence of free radical modification of proteins over the six months [ 54].
Other less obvious yet nonetheless radical modifications of the larval skull and hyobranchial apparatus (that is, the part of the skeleton that serves as base for the tongue on the floor of the mouth) occur to make room for newly developed sense organs.
More radical modifications of the correspondence theory push the recursive strategy even further, entirely discarding definitions like (1) or (2), and hence the need for atomic truthmakers, by going, as it were, "subatomic".
