Exact(5)
A colorimetric protein phosphatase inhibition assay (PPIA) utilizing protein phosphatase 2A and p-nitrophenyl phosphate as substrate, was applied in microplate format in order to serve as a quantitative screening method for the detection of the toxic activity associated with cyclic peptide hepatotoxins, at concentration levels >0.2 μg/L of MC-LR equivalents.
The developed method was validated in accordance with EU Commission Decision 2002/657/EC for a quantitative screening method, because this includes the WADA validation criteria and more.
In this work a quantitative screening method using high-resolution liquid chromatography in combination with accurate-mass time-of-flight mass spectrometry was developed and validated for determination of glucocorticosteroids, β2-agonists, thiazide diuretics, and narcotics and stimulants in urine.
This paper describes the development and validation of a quantitative screening method based on UPLC TOFMS for analysis of 56 restricted substances that are not very suitable for detection with GC MS methods, including corticosteroids, β2-agonists, and diuretics.
The objective of this study was to demonstrate a quantitative screening method to detect occurrence of relative ratings or comparison effects prior to an anticipated statistical analysis of large data files containing ratings from multiple raters.
Similar(55)
Strategy: "Rather than use a quantitative screen that prioritizes our research, as most longfund managers do, we make decisions about where to spend our time based on the investment merits of industries and subindustries.
We applied a quantitative screen for alterations in the pre-ribosome association to all 75 yeast snoRNAs in strains depleted of eight putative helicases implicated in 40S subunit synthesis.
Papers were excluded because: ineligible environment (i.e., not childcare; n = 8), absence of a quantitative screen-viewing assessment (n = 16), non-primary research (n = 12), ineligible age ranges (n = 4), failure to differentiate between screen-viewing accumulated at home versus in childcare (n = 7), and duplicated/repeated findings (n = 2).
As a consequence, quantitative screening of biothiols can be achieved.
A primary qualitative screening on solid plates containing carboxymethylcellulose as the substrate allowed selecting 2200 active clones that were then subjected to a secondary quantitative screening towards AZO-CMC for the selection of 76 improved variants that were cultured in flasks and characterized.
The latter segregants were then subjected to a comprehensive quantitative screening in liquid synthetic medium using the Growth Profiler.
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