The phrase "a puzzling feature" is correct and usable in written English.
You can use it when describing an aspect of something that is confusing or difficult to understand.
Example: "The study revealed a puzzling feature of the data that researchers could not explain."
Alternatives: "a perplexing aspect" or "an enigmatic characteristic".
Having the sequence of units in DNA determine the placement of nucleosomes would explain a puzzling feature of transcription factors, the proteins that activate genes.
It is a puzzling feature of the argument of Metaphysics IV 4 that distinctive properties are not explicitly mentioned.
Our skeletochronological data also identify a puzzling feature of this endangered lizard's life history: its low adult survival rate.
A puzzling feature of the 3' transduction events is that the sequence transduced is unique in the reference genome.
A puzzling feature of d-type crypts is that they are invisible before decolorization, although they are supposed to be stained by MB.
Finally, I would like to speculate on a puzzling feature of bacterial genomes that may have a role in the process of accumulating information.
A second puzzling feature was that many of the disease-linked SNPs did not occur in the DNA that codes for genes, but rather in the so-called junk regions of the genome.
From the earliest cloning and characterization of classical sequence specific transcription factors, a striking yet puzzling feature was the discovery of simple repetitive largely unstructured amino acid motifs (i.e., Gln-rich, Pro-rich, acidic repeats) that serve as 'activation domains' (ADs) coupled to DNA binding domains (Courey and Tjian, 1988).
Hubble pointed out an important and puzzling feature of the resolvability of M31.
One puzzling feature is that the entropy of a black hole scales with its area rather than with its volume, since entropy is normally an extensive quantity that scales linearly with the volume of the system.
One puzzling feature of McTaggart's mereological system is his apparent acceptance of a form of relative identity: x and y might be the same substance while simultaneously being different groups.
