We present the results of a prospective, observer-blinded, single-center case control study using a "pre post" design including 89 ambulatory patients with RRMS and an EDSS score of ≤ 3.5 who participated in an individualized 12 month aerobic endurance exercise program.
Under a randomized, prospective, observer-blind study design, subjects were sorted by random numbers into two groups.
This is a prospective, randomized, observer blind, active control, parallel group, multicenter, phase II study.
DECIDER is a prospective, randomized, observer blind, parallel group, multicenter, Phase II study with a 2x2 factorial design.
The ROSSINI Reductionn Of Surgical Site Infection using a Novel Intervention) trial was a prospective, multicentre, observer blinded, randomised controlled trial with stratification according to baseline infection risk.
The investigation was carried out as a prospective, randomised, observer blinded, controlled trial, according to the guidelines of the consolidated standards of reporting trials (www.consort-statement.org).org
This was a prospective, randomized, observer-blind control study.
A prospective, randomised, observer-blinded, cross over study was performed to investigate the effect of 2 mg repaglinide on hyperglycemia and endothelial function during an oGTT (75 g glucose dissolved in 300 ml water).
All six patients were recruited from a Mestizo-Mexican population in a previous cross-sectional, prospective, observer-blind study carried out between November 1995 and August 1997 [ 4].
Study Design: Prospective, observer-blinded, pilot randomized clinical trial.
