The phrase "a prospective marker of" is correct and usable in written English.
It can be used when discussing something that may indicate or predict a future outcome or condition.
Example: "The study aims to identify a prospective marker of early-stage Alzheimer's disease."
Alternatives: "a potential indicator of" or "a possible sign of".
Second, although the Köhne risk index and the use of a consolidative approach seem to have a stronger effect on patients' outcome as compared with the GSTP genotype, consolidative procedures cannot be used as a prospective marker for up-front determination of therapy benefit.
The strength of the preliminary evidence has a major role in the design of a prospective marker validation trial.
Similarly, the increase in incident prostate cancer observed in a Swedish cohort of MetS males was associated with high SUA and insulin levels, and both SUA and insulin were significant parallel prospective markers of risk for prostate cancer.
CD133, a recently reported prospective marker for CSC, is expressed in a variety of tumours.
Limiting the amount of crosstalk in prospective markers is of major importance, because it will allow the imaging of dense samples without prior bleaching.
Whilst the numbers are relatively small, there does not appear to be any reliable prospective marker, including the presence of spontaneous collateral channels on diagnostic angiography, to indicate which patients will fail medical therapy and require revascularisation.
The study "A prospective evaluation of surrogate markers for disease and relapse or reinfection in adult patients with pulmonary tuberculosis" was approved by the Stellenbosch University Health Research Ethics Committee (Ref no 99/039) and Cape Town City Health.
The identification of prospective markers has also been informed by advances in the genetics of Parkinson disease, for example the use of SNCA or DJ-1.
However, in the case of breast cancer, the rationale for selection of prospective markers is less clear, primarily because the human breast stem cell has not yet been extensively characterized.
In this study, we validated the prognostic value of clinical, histopathological and molecular markers in a prospective cohort of patients treated according to the multicenter HIT2000 medulloblastoma trial.
