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Taken together, there is a clear need for more research on the conditions (i.e., moderating variables) that make dampening a detrimental factor in the course of depression, given that some studies do and others do not observe a prospective link between dampening and depression.
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Moreover, our findings are in line with recent prospective evidence showing a link between a weak SOC and an increased risk of disability pension among employees =<50 years of age in entry of study [ 19], although it should be noted that most of the principal causes for disability pensions are not directly related to diabetes.
The data are also consonant with results of a large prospective cohort that found a link between hospitalization, particularly involving ICU admission, and subsequent cognitive decline and even dementia [ 14].
These findings represent the first prospective evidence demonstrating a causal link between disease processes in schizophrenia and nicotine addiction.
These results from Swedish prospective studies indicated a possible link between psychosocial background factors and early death due to accident and suicide [ 12].
Although the combined data from our retrospective and prospective studies suggest a strong link between an increased rate of enterococcal colonization and the winter/spring period, a causal relationship between time of the year and an increased rate of antibiotic use in the population cannot yet be conclusively drawn.
Until further prospective studies clearly delineate a causal link between lipid abnormalities and outcomes, it appears prudent for practitioners to continue to address lipid abnormalities in this population but to keep sustained emphasis on glycemic control, too.
For example, numerous prospective studies have shown a link between fresh and marine water exposure through swimming and gastrointestinal illness.
These issues remain a matter of debate, indicating a need for vast prospective studies to look for a causal link between osteoporosis and atheroma.
Prospective studies have failed to define a causal link between NSAIDs and invasive GAS infections (3 ), though such studies were not specifically designed to investigate this relationship.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com