Sentence examples for a pronounced defect from inspiring English sources
Together, these results suggest that the absence of dmtA transcript results in a pronounced defect in early sexual development.
Mouse cells with a deletion of the Ledgf (Psip1) gene have been engineered and show a pronounced defect in lentiviral infection and no effect on retroviral infection [36].
Cell wall plasticity is involved in daughter cell separation and mutant strains deleted for two of the major Staphylococcus aureus cell wall hydrolase genes (atlA and sle1) harbor an abnormal rough cell surface and a pronounced defect in cell separation [20], [21].
The decreased number of detectable tumors could also reflect a pronounced defect in tumor growth.
FZO1, MGM1 and UGO1 deletion strains fail to grow on non-fermentable carbon sources and galactose irrespective of LRRK2 expression indicating a pronounced defect in mitochondrial respiration (Fig. 9B).
The ichthyosiform phenotype of DCS most closely resembles non-bullous congenital ichthyosiform erythroderma and is characterized by a pronounced defect in the permeability barrier function of the skin leading to an increased transepidermal water loss.
However, the expression of TT788/89AA or Y783/795F mutants in GD25 cells did not rescue the capability of C. jejuni to invade these cells; especially the FAK-signaling deficient GD25β1A-Y783/795F cexhibitedbited a highly pronounced defect for the uptake of bacteria.
The pronounced defect of the Cik11 521 mutant points to an essential role for the non-catalytic head in the motility mechanism.
Ultrasmall CdSe nanocrystals are reported to exhibit pronounced defect emissions from surface trap states, which can be altered by the attachment of phosphonic acid ligands.
Gp93 mutant larvae display pronounced defects in the midgut epithelium, with aberrant copper cell structure, markedly reduced gut acidification, atypical septate junction structure, depressed gut motility, and deficits in intestinal nutrient uptake.
In the absence of zygotic γCOP activity, embryos die late in embryogenesis and display pronounced defects in morphogenesis of the embryonic epidermis and of tracheal tubes.
