The pro-apoptotic effect of restored GR expression in SCLC cells in vitro and now in vivo is a novel and exciting finding, and a deeper understanding of the mechanism whereby GR causes apoptosis in these cells offers a great promise for developing more selective and efficacious therapeutic agents.
The current attempt of using various algorithm-based and network-based computational tools for optimizing molecular synergy of herbal formula and elucidating their target network seems promising, which would also be a promise way for developing network-based multi-component drugs.
Among all microfabricated pumps, the electroosmosis-based pump shows the most promise for developing a high-pressure pump on a chip.
Because the miR-10b antagomir prevents metastatic dissemination but does not affect the late stages of the metastatic process after tumor cells have already disseminated, the main promise for developing an agent such as antagomir-10b as a potential therapy would be whether it can be added during treatment starting in the early stages as a prophylactic therapy against future metastasis formation.
Our pilot study suggests CGP holds great promise for developing a viable CAD system more suited to breast screening and so warrants further evaluation.
The present study demonstrates that the evolved R. opacus strain shows significant promise for developing a cost-effective bioprocess to generate advanced renewable fuels from mixed sugar feedstocks supplemented with glycerol.
Whilst still being at the beginning of a new era in drug discovery, it is clear that the information that is accumulating concerning the basic mechanisms that govern the cell cycle offers new hope and promise for developing a novel class of future medicines that specifically target aberrant proliferation.
The electrode showed good analytical performance and high selectivity with no interference from other oxidable species, demonstrating its promise for developing an effective glucose sensor.
The results hold promise for developing the model into a biocontrol agent to assist malaria control.
Most importantly, given their important roles in skeletal muscle, miRNAs hold great promise for developing effective therapeutic interventions for a wide range of muscle diseases.
