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'a prominent gap' is a correct and usable expression in written English.
You can use it to refer to a noticeable difference between two things, either physical (an obvious gap) or abstract (a large discrepancy). For example: "The survey results revealed a prominent gap between the opinions of men and women."
Exact(9)
However, well data show a prominent gap of several million years between the Upper Jurassic and Lower Cretaceous.
Mr. Lighty arranged a prominent Gap commercial for LL Cool J in 1997, and also struck endorsement deals for his clients Busta Rhymes (with Mountain Dew) and A Tribe Called Quest (with Sprite).
The inner edge of the Cassini division, a prominent gap of lowered particle density in the main rings, has an orbital period close to one-half of that of Mimas, and this gap is thought to be formed at least in part by resonant interactions of ring particles with the moon.
Widening of the scapholunate interval on imaging has been called the "Terry Thomas sign", referring to the famous actor with a prominent gap in his front teeth [11].
We strolled in to find a handsome Polish man with a prominent gap between his two front teeth standing behind a counter.
Hole-in-the-Wall used to be a prominent gap in the stone wall on the top of the ridge where a gate was missing.
Similar(51)
(Saturn's equatorial radius is 60,268 km [37,449 miles].) It is separated visually from the outer major ring, the A ring, by the Cassini division, the most prominent gap in the major rings.
Thermodynamic calculations indicate that within certain composition range in the V-Ti system, a prominent miscibility gap exists and the propensity for phase separation decreases with the addition of Cr in the binary system.
At the same time, there is a prominent pay gap between male and female workers with disabilities - an earnings ratio of 68percentt.
At the time the project was initiated, clinicians perceived a high demand for antimicrobial agents and displayed prominent gaps in knowledge regarding outpatient antimicrobial agent use for URIs and bronchitis (4, 25– 25).
There was a clear loss in cell motility as reflected by prominent gaps in the scratches made in PAX8 knock down plate compared to control cell monolayer.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com