She has announced that "coal will remain a pillar of German energy supply for a prolonged time span".
That means we are spending more years living with chronic disease and ill health — not the outcome that most of us would hope for from a prolonged life span.
The study revealed that the life span of a personal computer has considerable influence upon the system, most notably in the following two aspects: (i) a prolonged life span creates value by means of refurbishing and upgrading activities, and (ii) it slows down the flow rate of the whole system.
While it's near-impossible to administer cannabinoids in the midst of a stroke or during suffocation, cannabinoids can intervene in cases where brain damage occurs over a prolonged time span.
Consistent with this C. elegans mutants daf-2, age-1, and daf-16 that possess a prolonged life span are not significantly different from wild type animals concerning their reproductive period [25], [26].
FIRKO mice with fat cell specific insulin resistance have a prolonged life span [ 57].
Similarly, mice with a mitochondrial-targeted overexpression of catalase demonstrate a prolonged life span with improved cardiac function [50] and an attenuation of cardiac aging [51].
The use of outside hospital records and the accuracy of patient records kept over such a prolonged time span may introduce information bias.
We are limited by the need for a prolonged time span used for patient accrual, during which radical changes in diagnosis and management may have influenced survival outcomes.
Here, we provide the first evidence that repeated OS causes gradual reductions in arterial oxygenation over a prolonged time span of 6 hours.
Subsequently, a prolonged life span of FLSs was recognized (reviewed in [ 68, 69]), although even a combination of enhanced proliferation of the normally slow growing FLSs plus defective apoptosis seems an insufficient explanation.
