However HIV-1 cannot be eradicated from infected individuals by current regimens and low levels of HIV-1 RNA in the plasma can be detected using extremely sensitive reverse transcriptase assays, even in patients on prolonged effective cART [1] [7].
PEG-GFL-NH-Ret has clearly shown several advantageous features over free Ret-NH2 for oral drug delivery, including sustained drug delivery, controlled pharmacokinetics, low drug concentrations in the systemic circulation, and prolonged effective protection against light-induced retinal degeneration.
Phenytoin can be used as an initial treatment for cessation of seizure activity, for maintaining a prolonged antiseizure effect following effective treatment with a benzodiazepine, or when benzodiazepines are ineffective.
A single dose of radiation during surgery is just as effective as a prolonged course of radiotherapy for breast cancer, a study suggests.
These results confirm that dilation with a large diameter dilator, i.e. multiple plastic stents, for a prolonged period is the most effective way to relieve benign strictures.
In particular, RA seemed to be more effective after a prolonged incubation period (24 h), inducing the highest IL-10 increase when added immediately after irradiation.
Therefore, CTCs could be very valuable in resolving the problem in which an inefficient chemotherapy regimen is administered to a CRC patient for a prolonged period or a potentially effective chemotherapy regimen is interrupted prematurely.
Although all the organophosphates evoked significant reductions in DNA synthesis, diazinon was the most effective over a prolonged time course: after 6 days of continuous exposure, diazinon maintained a significantly greater inhibitory effect than did either chlorpyrifos or parathion.
The literature has focused on many properties considered by women when selecting a contraceptive method, such as whether a contraceptive method is highly effective, has a prolonged duration of action, is rapidly reversible, protects against sexually transmitted diseases, is easily accessible, is convenient/easy to use, and poses little to no side effects, risks, or disadvantages [ 21, 22].
The question, "Is a prolonged period of antithrombotic pretreatment effective for reducing adverse outcomes in patients with unstable coronary syndromes?" returned close to 40,000 citations, but when rephrased to, "Is prolonged antithrombotic treatment indicated in unstable coronary syndromes before intervention?" the first citation was an exact match.
