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More importantly, the in vivo pharmacodynamics demonstrated that the orally delivered system induced a prolonged decrease in blood glucose levels among diabetic rats.
This short-term food intake was immediately followed by a prolonged decrease in food ingestion, correlating with an observed delay in emptying of the stomach leading to a sensation of satiety.
OBJECTIVE Exposure to trauma-related cues has been associated with a prolonged decrease in heart rate variability (HRV) under laboratory conditions, however the relationship between PTSD symptoms and HRV has not been evaluated during everyday life.
Murzi and colleagues [ 59] demonstrated in 14 patients a prolonged decrease in thyroid hormones for five to seven days.
Creatinine showed a good correlation with LDH activity over time but exhibited a prolonged decrease before reaching the reference range.
This phenomenon of p53 upregulation followed by a prolonged decrease was also observed in HeLa cells (Supplementary Figure 2a).
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In contrast, Type A men showed a more prolonged decrease in electrocardiographic T-wave amplitude (TWA) than did Type B men. Post hoc analyses of the correlates of TWA recovery during high-dose ISO infusion provide preliminary evidence for a more robust parasympathetic antagonism of sympathetic nervous system effects in Type B men, especially those with low scores on the Cook-Medley Ho scale.
The i.v. injection of radiographic contrast medium causes an initial increase in renal blood flow that is then followed by a more prolonged decrease in blood flow and accompanied by a decrease in glomerular filtration rate (GFR), while the extrarenal vessels show transient vasoconstriction followed by a decrease in vascular peripheral resistances.
The intravenous injection of radiographic contrast medium causes an initial increase in renal blood flow but is then followed by a more prolonged decrease in blood flow and accompanied by a decrease in glomerular filtration rate (GFR), while the extrarenal vessels show transient vasoconstriction followed by decrease in vascular peripheral resistances.
However, in contrast to pamidronate, ZA induced a more prolonged decrease in serum vascular endothelial growth factor up to 21 days after the infusion.
Our results revealed a significant and prolonged decrease of RBF in OM and CO and also a decreased oxygen level in OM after CM injection, indicating that ASL and BOLD MRI are potentially useful in the clinic for noninvasive assessing of renal function in the case of CIAKI.
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