The phrase "a proliferating potential" is correct and usable in written English.
It can be used to describe the capacity for growth or increase in a particular context, such as in business, technology, or biology.
Example: "The research indicates that this new technology has a proliferating potential that could revolutionize the industry."
Alternatives: "an expanding capability" or "a growing potential".
Open image in new window Fig. 1 Cultured rabbit MSCs showed a classical, long fusiform shape and a high proliferating potential that caused them to easily undergo confluence Open image in new window Fig. 2 MSCs induced for 7 days with a mixture of osteogenetic inducer of 50 mg/L ascorbic acid, 10 mmol/L β-glycerophosphate and 10−8 mol/L dexamethasone.
Thus, a structurally-stable cell nucleus would not be the seat of both the dynamic transitions necessary for mitosis and the rearrangements of chromosome territories and chromatin domains in early G1 [ 98] that normally occur in cells with a positive proliferating potential, since the energy cost of nuclear disassembly and reassembly will be limiting for the cell.
We measured the standard parameters describing CA and found an elevation in the superoxide level, percentage of death cells, the level of TUNEL positive cells and a decrease in proliferating potential.
The interactions between DNA and the NM define a higher-order structure (NHOS) in the interphase nucleus., Classical studies have shown that normal cells with proliferating potential lose such a potential in a stochastic and non-reversible fashion independently of their previous number of cell divisions thus achieving a state of replicative senescence.
However, single-cell cloning studies with normal human fibroblasts revealed a bimodal distribution in the replicative potential of clonally derived cells, indicating that there is a stochastic loss of cell proliferating potential [ 28- 30].
For addressing this question let us consider the fact that both RS and STASIS are non-reversible at least in human cells [ 3, 5] and yet RS can by bypassed in human tissues with proliferating potential by a number of mechanisms such as reactivation of telomerase, leading to cell immortalization as a precondition for tumorigenesis [ 5, 22].
However in healthy but older animals the fraction of remaining hepatocytes able to re-enter the cell cycle after liver injury is reduced to < 70%., This spontaneous loss of proliferating potential as a function of age has been linked to the terminal differentiation of the hepatocytes.
It is a fact that malignant tumours can only arise in tissues with proliferating potential hence tissues with a large proportion of post mitotic cells such as the brain and the heart are rarely the seat of malignant tumours and the tumours derived from such tissues arise from cells with proliferating potential like the brain glia or the vascular endothelium [ 23, 24].
Bansal et al. [ 8] justified this low tendency to progress with the probability that the cells already present at the interface have limited proliferating potential and die after a few mitotic divisions, leaving amorphous debris seen clinically as a homogeneous white mass.
The MSCs we cultured showed a uniform fibroblast-like appearance as well as high proliferating potential (Fig. 1).
