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This review analyses key aspects of that progression of models, against a background of what exactly each model system tries to mimic.
These observations and data in the literature led to a progression model of breast cancer (Fig. 1) based on early genetic alterations [ 17].
Accumulating pathological and epidemiological evidence supports a progression model of MOC, from benign cysts to borderline tumours to invasive adenocarcinoma (Feeley and Wells, 2001; Shih and Kurman, 2004).
For us jaded adults, the long-running trend toward making apps and games free to download but stuffing them with paid options is just an annoyance or perhaps a logical progression of the business model.
The previous scenario we proposed [ 9, 14], implying a northwards progression of the species (model 1, Fig 2), fits well with published reports that place the origin of C. aspersum in north Africa [ 8].
You characterize the move into self-publishing as a natural progression of the current business model, but it's also fairly innovative.
Hence apigenin is a potent inhibitor of cell-cycle progression in a variety of model systems of leukemia growth.
However, later work has directly tested the role of Myc signaling in metastatic progression using a variety of model systems.
Our lab has recently evaluated EPLIN involvement in cancer progression in a number of model systems [ 10– 10].
There are a number of obvious distinctions between the progression of a pathway model and the progression of a software project.
Furthermore, the identification of non-invasive precursor lesions of pancreatic adenocarcinoma has led to the formulation of a multi-step progression model of pancreatic cancer and the subsequent identification of early and late genetic alterations culminating in invasive cancer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com