This year, almost half a century since the first gay pride parade in 1969, it goes without saying that pride celebrations have profoundly evolved in meaning and execution.
The care of rheumatoid arthritis (RA) has profoundly evolved during the last decade because of new drug therapies and the early treatment paradigm.
We've lived in a constantly evolving relationship with machines that has profoundly affected how we see human nature.
He revived the Ford Thunderbird, which had evolved from a noble creature to a profoundly ugly duckling, by giving it a stylish makeover.
Mariska's Joyful Heart Foundation has evolved into a major force in helping women to heal from unspeakable trauma and abuse in a profoundly caring and sensitive way.
If a riot evolves as it spreads, starting with the hotheaded rock thrower and ending with the upstanding citizen, then rioters are a profoundly heterogeneous group.
A profoundly important book.
A profoundly shameful betrayal.
It is a profoundly bleak analysis.
And, on Tuesday, a profoundly introspective one.
It's a profoundly un-educational message.
