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A profound skepticism has taken root in some of the largest trading powers, notably the United States, France, Italy and Japan.
Like Diderot in the 18th C. Dr. Di Bona has maintained a profound skepticism concerning the benefits of institutional solutions to daily problems.
Realism, by contrast, sports a profound skepticism about the application of moral concepts, such as justice, to the key problems of foreign policy.
As a child, my proximity to art imbued in me a profound skepticism.
The two leading Democratic candidates in next Tuesday's New Hampshire primary share a profound skepticism for ideas many in the party have long held dear.
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But he's also responsible for a film that, despite profound skepticism and a distinct lack of men in capes and tights, grossed a whopping $51.1 million in its opening weekend during the height of superhero season.
Under pressure from Prime Minister Tony Blair of Britain, Mr. Bush agreed to publish a "road map" for a peace attempt, but he still faces profound skepticism from those who think American-Israeli ties preclude an evenhanded effort.
"Naomi's and Avi's profound skepticism is not a skepticism I share, even though they have far more evidence than I do," he says.
This series starts with "The Sun's Burial," his wide-screen 1960 melodrama of wayward youth, which, while it does not establish a formal pattern for his subsequent films, lays out some of his characteristic themes: a profound, angry skepticism about Japanese politics and society; an interest in the agonies of the young; and a taste for emotional extremity.
But there is cause for profound skepticism as well.
But from the outset they have expressed profound skepticism of claims by Dr. Fleischmann and Dr. Pons.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com