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'a profound sense' is a perfectly correct and usable part of a sentence in written English.
It is typically used to describe a feeling or emotion that is intense and deep. For example, "The kindness of strangers filled me with a profound sense of gratitude."
Exact(59)
There remains a profound sense of perspective among the fans.
They also have a profound sense of personal dignity.
Underlying this denial is a profound sense of entitlement.
"They taught me a profound sense of social consciousness".
Suddenly, a profound sense of ennui envelopes the table.
That point of view encompassed a profound sense of place.
We are left with a profound sense of loss.
I think he has a profound sense of being alone.
It fills me with a profound sense of sorrow".
And instead of fine wines, beer — but good beer, with a profound sense of place.
"There was a profound sense of injustice about what had been happening here," Mr. Bour said.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com