'a profound role' is a correct and usable part of a sentence in written English.
You can use it to describe the impact of something. For example, "The teacher played a profound role in my development as a student."
America's allies have a profound role to play right now.
Church leaders say a survey reinforces the idea that the chapel has taken on a profound role as a shrine.
Two sounds played a profound role in the creation of his symphony, Sir Peter explains, and they once again evoke the pattern of an eerie landscape contrasted with the human attempt to master it.
Matrix stiffness plays a profound role on stem cell behavior.
Finally, geometry plays a profound role in all of the STEM disciplines.
NaCl has a profound role on microbial development influencing cheese sensory and technological properties.
For example, shifting what we eat could also play a profound role.
Clouds, as one of the major meteorological phenomena, play a profound role in climate predictions and services [1, 2].
Workflow repositories and libraries have a profound role in achieving this objective by providing the enabling environment.
Of particular interest is apoptosis which has a profound role within tumor development and has significant effect on cancer malignancy.
Along with scientific models and analogies, metaphor plays a profound role in shaping our ideas about the world around us.
