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The phrase "a profound restructuring of" is correct and usable in written English.
It can be used when discussing significant changes or transformations in an organization, system, or process.
Example: "The company is undergoing a profound restructuring of its management hierarchy to improve efficiency and communication."
Alternatives: "a significant overhaul of" or "a major reorganization of".
Exact(7)
If Mr. Buffett feels grateful for having been rescued by taxpayers' money he should show his appreciation by advocating a profound restructuring of a financial industry completely run amok.
There can be no true democracy in the Middle East without a profound restructuring of economic priorities, which in turn can come about only by combating corruption, limiting the prerogatives of the military, and, above all, reconsidering economic relations with other countries and the gross inequalities of wealth and income within Muslim countries.
Striving to become a stronger regional center, Nanjing is undergoing a profound restructuring of its economic and, more importantly, its physical form and appearance.
Also the GABAergic input expands its territory of innervation on the proximal domain, which undergoes a profound restructuring of the glutamate and GABA receptors.
While striving to become the new economic power house of western China, Lanzhou is undergoing a profound restructuring of its economic and, more importantly, its physical form and appearance.
While striving to become the new economic power house of western China, Urumqi is undergoing a profound restructuring of its economic and, more importantly, its physical form and appearance.
Similar(52)
It is in the midst of a profound restructuring, with the largest participants merging and vast government funds being used to lubricate the transition.
"FIFA needs a profound restructuring," he conceded at a brief news conference in Zurich on June 2nd.
But the country is going through a profound restructuring in moral and economic thinking and the danger for Republicans is that their current coalition might become obsolete.
"FIFA needs a profound restructuring".
They have recommended a fundamental restructuring of the railways.
More suggestions(13)
a profound realignment of
a significant restructuring of
a profound reordering of
a severe restructuring of
a thorough restructuring of
a thoroughgoing restructuring of
a profound reshaping of
a fundamental restructuring of
a profound reorganisation of
a substantial restructuring of
a considerable restructuring of
a radical restructuring of
a far reaching restructuring of
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com