Sentence examples similar to a profound obstacle from inspiring English sources

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Income inequality is a similarly profound obstacle to progress in Russia, with some reports suggesting that Russia's wealth gap is the worst in the world.

According to Deryabin, there was also a more profound obstacle – Russia's surprising indifference to the genius behind War and Peace, Tolstoy's contrapuntal saga set during the years of Napoleon's wars in Europe and his invasion of Russia.

There is another, more profound obstacle facing the relaunch of Brand USA: the values Beers is charged with selling are democracy and diversity.

More Muslim women are taking up active roles in the debate, but they are up against some profound obstacles - as much from within as from outside Muslim communities.

G protein-coupled receptor (GPCR) instability represents one of the most profound obstacles in the structural study of GPCRs that bind diffusible ligands.

Refreshingly, at the end of the day these girls, even though they are acting mature beyond their years, are overcoming profound obstacles and are setting the path for girls in their communities for years to come, they are still young girls at heart.

There was a profound awareness of the challenges overcome, yes, but also the obstacles -- and internal divisions -- to be faced if the country is to move forward.

As a viable solution to such obstacles, advances in nanoparticle surface engineering augmented by a profound understanding of cancer physiology present new opportunities for MNP-based imaging and therapeutic agents.

There is, in our experience, a profound culture gap between the publishing industry and the film industry, thus creating obstacles that are not inherently necessary to high quality minds who might otherwise be interested in the medium.

However, there is little research on facilitators and obstacles to the transition to adulthood, and impacts on people with a profound ID.

Hypoglycaemia of any severity has a profound effect on patients' quality of life [ 7] and is regarded as the single greatest obstacle to achieving normoglycaemia [ 10].

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