a profound modification of

USAGE SUMMARY

The phrase "a profound modification of" is correct and usable in written English.
It can be used when discussing significant changes or alterations to something, often in a formal or academic context. Example: "The research revealed a profound modification of the existing theories in the field of psychology."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

2 human-written examples

"I had these big boxes — shoeboxes — full of clippings, and, like that, I saw that something was happening, a profound modification of our society, and that no one was noticing, or they were noticing but not really saying anything about it".

The New Yorker

Different spectroscopic techniques, FT-IR, 13C {1H} CP-MAS NMR and Raman, applied to characterize the formed networks, describe a profound modification of the chemical structure when network size is approaching the nanoscale.

Polymer

Human-verified similar examples from authoritative sources

Similar Expressions

58 human-written examples

The object we are accustomed to calling a book is undergoing a profound modification as it is stripped of its physical shell.

The New York Times

So no matter how much Randall Stross says that the book is going through a "profound modification as it is stripped of its physical shell," you sure as heck better not whip it out when the seatbelt sign is on, something that amounts to a fatal flaw for the avid reader.

TechCrunch

Modification of metazoan histone variant lineages occurs on a background of genome architecture that shows global similarities from sponges to vertebrates, but the urochordate, Oikopleura dioica, a member of the sister group to vertebrates, exhibits profound modification of this ancestral architecture.

BMC Evolutionary Biology

The next generation of polymer conjugation technology enables more complex and profound modification of cytokine activity.

Cytokine

Two force-distance curves recorded between the silicon nitride probe and the surface of the BMDCs were shown in Figure 5. Force-distance curve measurement demonstrated that the changes in the immature or mature BDMC surface nanostructure went along with profound modification of the nanomechanical property.

Nanoscale Research Letters

CARS is characterized by reduced in vitro lymphocyte proliferation [ 3], reduced ex vivo cytokine production upon activation of monocytes and neutrophils by endotoxin (lipopolysaccharide, LPS) [ 4, 5], reduced Natural Killer (NK) cell activity [ 6], enhanced apoptosis of lymphocytes and dendritic cells [ 7], and profound modification of different cell surface markers.

Critical Care

In addition, the pattern of ecosystem demands shows a levelling of rural urban gradients, reflecting profound modifications of traditional rural urban relationships.

Land Use Policy

There, he writes that "even in those countries which give legal sanction to the festive character of Sunday, changes in socioeconomic conditions have often led to profound modifications of social behavior and hence of the character of Sunday".

The New York Times

These data suggest that glucose induces profound modifications of the monocyte pro-inflammatory response.

Critical Care

Expert writing Tips

Best practice

When using "a profound modification of", ensure that the context clearly indicates what is being modified and the nature of the modification. This phrase is most effective when emphasizing the significance and depth of the change.

Common error

Avoid using "a profound modification of" for minor or superficial changes. This phrase implies a deep and significant alteration, so ensure the scale of the change warrants such strong language.

Linguistic Context

The phrase "a profound modification of" functions as a noun phrase, typically serving as the object of a verb or the complement of a preposition. It describes a significant change or alteration to something, as evidenced by Ludwig's examples.

Expression frequency: Rare

Frequent in

Science

60%

News & Media

30%

Encyclopedias

10%

Less common in

Formal & Business

0%

Wiki

0%

Reference

0%

Ludwig's WRAP-UP

In summary, the phrase "a profound modification of" is a grammatically correct and usable English phrase that signifies a deep and significant alteration. As Ludwig AI explains, it is best suited for formal contexts such as scientific or academic writing, where the emphasis is on the substantial nature of the change. While relatively rare in overall usage, it is most frequently found in scientific and news media sources. When using this phrase, ensure that the context warrants the emphasis on the depth of the modification, and consider alternatives like "a significant alteration to" for similar but potentially less emphatic meanings.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

a fundamental alteration of

Emphasizes that the change is basic and essential.

a significant alteration to

Focuses on the importance of the change, with 'alteration' indicating a change in character or composition.

a deep transformation of

Emphasizes the thorough and far-reaching nature of the change as a complete change.

a radical shift in

Suggests a fundamental change in approach or direction.

a dramatic change in

Highlights how striking the changes are.

a major revision of

Highlights the act of reviewing and altering something, often to improve it.

a substantial adjustment to

Implies a considerable change made to better suit a particular situation.

a sweeping change to

Indicates a broad and extensive alteration affecting many things.

a complete overhaul of

Indicates that something has been entirely rebuilt or reorganized.

a groundbreaking adaptation of

This implies an innovative approach to change, setting a new standard.

FAQs

How can I use "a profound modification of" in a sentence?

Use "a profound modification of" to describe a significant and impactful change to something. For instance, "The new policy represents a profound modification of the company's approach to environmental responsibility."

What are some alternatives to "a profound modification of"?

Alternatives include "a significant alteration to", "a deep transformation of", or "a radical shift in", depending on the specific context.

When is it appropriate to use "a profound modification of" versus "a slight change to"?

"A profound modification of" is appropriate when the change is substantial and impactful, affecting fundamental aspects. "A slight change to" is suitable for minor, superficial adjustments.

Is "a profound modification of" formal or informal?

"A profound modification of" is generally considered a formal phrase suitable for academic, scientific, or professional contexts. More informal alternatives may be better suited for casual conversation.