Sentence examples similar to a profound modification in from inspiring English sources

The object we are accustomed to calling a book is undergoing a profound modification as it is stripped of its physical shell.

A similar profound modification in energy metabolism genes has been observed in thyroid oncocytomas, with high activity of the aerobic respiratory pathway [ 24].

The p-OH modification of the phenacyl chromophore causes a profound change in the photochemical behavior.

It was potentially a profound change in federal state relations.

Hypoxia induces a profound change in the phenotype of macrophages.

We use daily data from 2010 to 2015, a period with profound modifications in the German electricity market, the most notable being the rapid integration of photovoltaic and wind power sources, as well as the phasing out of nuclear energy.

Profound modifications in gene expression were observed in ST260-261 strands and to a lesser extent in strain CF01173 compared to strain A909.

Profound modifications in the relationships between cytokines or Hsp and changes in muscle parameters were observed in the piroxicam group.

Thus, the antifibrotic phenotype observed in fibroblasts submitted to proteasome inhibition results from profound modifications in the binding of key transcription factors.

Thus, healthy normal tissues that, for physiological or pathological causes, undergo remodeling are subject to profound modifications in ECM components in response to the mutated physiological requirements.

Twenty-three oft of 42 criteria were significantly associated with Y. pestis infection, reflecting the profound modification induced in the DLN by this bacterium.