Sentence examples for a profound limitation from inspiring English sources

As Richard Feynman pointed out, Fredkin's notion of modeling nature as a reversible cellular automaton had a profound limitation: it failed to account for quantum processes.

Even if the law is neutral with respect to the particular points of view expressed, it is still a profound limitation on individual liberty.

Hence, a profound limitation of the analysis is that it does not consider the broader contribution of the individual to the country's economic growth and the future increased demand for goods and services.

While some of these values and beliefs enable creative achievement and success, others create a sense of profound limitation and self-doubt.

Australian data indicate that close to one quarter of people aged over 65 years report a severe or profound limitation of core activities (self-care, mobility or communication) and that 84% of these people report mobility limitations.[ 3] There is increasing evidence that this mobility-related disability in older people can be reduced by well-designed exercise programs.

This profound limitation in sensitivity can be overcome by enzymatically releasing the exact SHL8 peptide from its embedded location within the polypeptide sequence.

In particular, the benefit of enhancing the statistical power can help to overcome the most profound limitation of microarray studies: testing tens of thousands of hypotheses, relying only on a relatively low number of samples (7, 8).

Our findings thus underscore the profound limitations and challenges of a dual HF-COPD diagnosis, contributing to our understanding of a population in which previous research has predominantly focused on epidemiology and diagnosis [ 11, 65].

Nevertheless, as described in the methods section, there were profound limitations in the data for a proper analysis of sex effects.

The third is the importance of learning in human organizations as an instrument of change and resistance to change and the profound limitations to the effectiveness of experiential organizational learning.

Hundreds of studies reveal the profound limitations of the traditional interview.