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Quite apart from the practical chaos that would result, should perhaps 20% of NHS doctors leave, the profound intolerance of this idea is breathtaking.
The final scene reminded me so much of Dr. Seuss' "The Butter Battle Book" (1984) and both had a profound impact on me about race and intolerance at a young age.
You are the only one who sees the necessity of a profound change of methods and is attempting it without intolerance, tyranny or destruction.
Alterations in the intrauterine milieu have a profound impact on glucose homeostasis in the offspring, culminating in the development of insulin resistance, glucose intolerance and type 2 diabetes in adulthood.
However, the administration of the same amount or even less in a patient with pre-treatment lactate intolerance (liver failure, severe septic shock) will induce a dramatic increase in lactate concentration and a profound acidosis.
Although some found Intolerance to have major inconsistencies, it was lauded by other filmmakers, particularly in the Soviet Union, as a profound influence on their works.
A profound stillness descends.
What a profound loss.
That's a profound contribution".
It's a profound collection.
This was a profound reversal.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com