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"We're witnessing a profound evolution in doctrine in the space of a lifetime, which doesn't happen often," he says.
Mr. Petraeus almost single-handedly forced a profound evolution in the country's military thinking and doctrine with his philosophy of counterinsurgency, focused more on protecting the civilian population than on killing enemies.
"This is a profound evolution in the landscape of trust from 2009 where business had to partner with government to regain trust, to today, where business must lead the debate for change," Edelman president and CEO Richard Edelman wrote in a press release about the Trust Barometer.
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February 2012 saw the birth of CKJ, a name change that was part of a more profound evolution in editorial policy [ 3].
These organisms play a profound role in evolution and ecology of our biosphere (primordial life on earth is believed by many to be thermophilic [ 2]).
Religiosity also makes a profound difference in acceptance of evolution (χ 2 = 990.54; df = 2; P < 0.001; Figure 3b).
To build business, individual artists catered to clients with "presumed or stated aesthetic concerns or expectations". The wealthy Italians and Spaniards living in Bruges, a city of great wealth, who had considerable amounts of expendable income had a profound effect in determining the evolution of the art market and even styles of painting.
The origin of life did not coincide with the organismal LUCA; rather, a profound gap in time, biological evolution, geochemical change, and surviving evidence separates the two.
At this time in history, the Western world held to a profound belief in progress, and evolution was seen as something that could be used to further human progress.
During the Neogene and Quaternary, tectonic and climatic processes have had a profound impact upon landscape evolution in England and, perhaps as far back as 0.9 Ma, patterns of early human occupation.
If early lake colonists were also philopatric, this 'preadaptation' would have had a profound influence on evolution of species diversity in the African Great Lakes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com