A significant proportion (13%) of people in Australia is now aged over 65 years [ 2], with almost one quarter of these older persons suffering from a severe or profound disability [ 3].
Moreover, when reducing DA doses, a withdrawal syndrome (DAWS) may occur in a subset of patients, causing profound disability [ 63].
In a small proportion of patients the disease may result in profound disability leading to a need for the provision of complex care and, for some people, information on planning around end of life care.
"He has a profound cognitive disability," Dr. Smith said.
Lynndie R. England, the Army reservist who admitted abusing Iraqi prisoners, her school psychologist testified that she suffered as a child from a profound learning disability.
The first 60-page section of Faulkner's landmark novel are presented through the eyes of Benji Compson, a man with a profound learning disability.
Although autism affects a broad range of skills, the Yale researchers consider its central feature to be "a profound social disability," in Dr. Klin's words.
But such a profound physical disability did not stop Mary from enjoying a fulfilling childhood.
The tales Solomon returns with, of profound disability and extreme differences overcome, make it a bible of empathy and inclusion.
The most disabled trajectories had severe disability at age 85 progressing to profound disability by age 90.
