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A profound difference between the two hapless suitors is that during his madness Patrick had a family to fall back on, a selection of confidantes and a blossoming career as a writer, whereas Bob has nobody and nothing.
There is a profound difference between the two countries' positions in practice.
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The tenth open issue listed by EFSA actually shows a profound difference between the Séralini study and the two others.
There are, after all, profound differences between the two parties when it comes to their views on budget priorities, on the relationship between taxes and economic growth, on the welfare state, and on the proper scope and scale of government.
Raul Castro sounded a cautious note, stressing that there were still "profound differences" between the two countries.
Ms. Thomas set an admirable example when she said the refusal to recognize profound differences between the two candidates had made her "come out fighting".
Because they speak volumes about the profound differences between the two men who delivered them.
"There are profound differences between the two of us," Bigosinski, then 41, said in the debate against Loughlin, who was 31 at the time.
There's a profound difference between earth (that thing under our feet) and Earth (a particular planet orbiting a particular star in one of many galaxies).
There is a profound difference between protecting a source and being played.
Badinter told me, "There is a profound difference between me and most other feminists.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com