The phrase "a profound degree of" is correct and usable in written English.
It can be used to emphasize the intensity or significance of a particular quality or characteristic.
Example: "The research revealed a profound degree of impact on the local ecosystem due to the new development."
Alternatives: "a significant level of" or "a deep extent of".
The most common mistake you hear attributed to Mosby is that she overcharged in the indictments, trying to establish such a profound degree of blame that it was impossible to prove.
They show both a profound degree of racism, as well as a rejection of Obama as an American.
This indicated that a profound degree of gene silencing had taken place subsequent to the initial activation of the spleen cells.
However, the lack of significant functional perfusion in PDA results not only from a sparse vasculature but also from a profound degree of vascular collapse.
A profound degree of disparity in the antibacterial activity of honey from the same floral source but from different geographical locations was also observed in this study as documented in other studies [ 21, 39, 40] (Table 4).
They also manifest a profound degree of insulin resistance and marked elevations in hepatic transaminases (indicative of hepatic steatosis) and triglycerides, which are greater in severity than in patients with commonly occurring T2DM lacking PLL.
Analysis of receptor function by an operational model indicated that with either treatment morphine could induce a profound degree (70 80%) of loss of receptor function.
In addition to this general biological variation for all of these housekeeping genes, a more profound degree of variation seems based upon the existence of isoforms which are present only in a subset of tissues.
An increased or even normal serum sodium concentration in the presence of hyperglycemia indicates a rather profound degree of free water loss.
As a result, as The Pacific progresses its emotional power strengthens to such a profound degree that we can feel the loss of each and every one of the Marines (and there are thousands) that are shown lying dead on the many beaches and jungle areas that became blood-soaked battlegrounds during those campaigns.
Living businesses — those that achieve this profound degree of relevance — will have pricing power and will drive repeat purchases.
