Sentence examples for a profound decrease of from inspiring English sources

Interestingly, the combination of sepsis and CAD demonstrated a profound decrease of eNOS expression, which may be due to the sampling since Lange et al. showed that eNOS is upregulated early in sepsis and then steadily decreases over time [52].

In addition, entecavir-induced suppression of viral replication resulted in an increase in Th17 cells and concomitant decrease in Treg cells, which was manifested by a profound decrease of the Treg/Th17 ratios.

Indirect immunofluorescence assay (IFA) revealed a profound decrease of influenza A proliferation in Mx1 transgenic cells.

Our data, however, demonstrated a profound decrease of cellular TAG when PE formation via the CDP-Etn pathway was blunted.

Prenatal endotoxin exposure in rabbits revealed similar results with a profound decrease of neurons in the anterior thalamus [ 8].

In patients with spinal cord injuries, a profound decrease of sublesional bone mineral density was measured in comparison with controls [ 2].

Application of the selective MOR agonist DAMGO (10 μmol L−1) resulted in a profound decrease in frequency of mIPSCs with no change in amplitude indicative of an action of DAMGO at MORs located on the nerve terminals of GABAergic afferents.

Concomitantly, Chile witnessed a profound decrease in levels of poverty and homelessness, which fell by 60% over a period of 20 years [ 22].

Figure 6A (control) and Figure 6B (Met-enkephalin-treated) show that 7 9 h of Met-enkephalin treatment results in a profound decrease in the ability of both a submaximal and maximal concentration of Met-enkephalin to inhibit eIPSC amplitude, indicative of desensitization of the MOR taking place during the 7 9 h treatment (pooled data shown in Figure 6C).

We assume that reduced expression of PLD3 is attributable to a profound decrease in total populations of neurofilament-positive neurons in AD brains, as reported recently [ 19].

This highly regulated cascade of events results in net extravasation of fluid, a profound decrease in systemic vascular tone, collapse of the microcirculation and subsequent distributive shock, acute respiratory distress syndrome (ARDS) and eventually multiple organ dysfunction syndrome (MODS) [ 1, 3- 5].