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Discover LudwigThe phrase "a profound decrease in the ability" is correct and usable in written English.
It can be used when discussing a significant reduction in someone's or something's capacity to perform a task or function.
Example: "The recent changes in policy have led to a profound decrease in the ability of the staff to meet project deadlines."
Alternatives: "a significant reduction in capability" or "a major decline in proficiency."
Exact(1)
Figure 6A (control) and Figure 6B (Met-enkephalin-treated) show that 7 9 h of Met-enkephalin treatment results in a profound decrease in the ability of both a submaximal and maximal concentration of Met-enkephalin to inhibit eIPSC amplitude, indicative of desensitization of the MOR taking place during the 7 9 h treatment (pooled data shown in Figure 6C).
Similar(59)
A profound decrease in free IGF-I suggests a reduced bioavailability of IGFs from plasma to the tissues.
"A profound decrease in slow-wave sleep had an immediate and significant adverse effect on insulin sensitivity and glucose tolerance".
By contrast, acute hypotensive anemia (saline hemodilution) resulted in a profound decrease in both brain and muscle tissue PtO2 and evidence of inadequate global perfusion (lactic acidosis).
Our data also demonstrated a profound decrease in IFNγsignaling in A20 overexpressing livers.
A profound decrease in β-agonist stimulated cAMP was found, which led to additional studies indicating a post-receptor phenomenon.
This decrease in BV/TV was primarily due to a profound decrease in trabecular number (p < 0.001).
Infection of both Caco-2 and LS174T cells with specific lentiviruses resulted in a profound decrease in Bim, resp.
Prenatal endotoxin exposure in rabbits revealed similar results with a profound decrease of neurons in the anterior thalamus [ 8].
By contrast, there was a more profound decrease in PvO2 and saturation in the saline hemodiluted group (Tables 1 and 2, Fig. 1, p < 0.05).
The proHGF treatment produced a more profound decrease in pluripotent genes and increase of differentiation genes than did the other experimental treatments (Figs. 2C, 2D, and S4).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com