The phrase "a profound decrease in" is correct and usable in written English.
It can be used when discussing a significant reduction in a particular quantity, quality, or condition.
Example: "The study revealed a profound decrease in biodiversity over the past decade."
Alternatives: "a significant reduction in" or "a substantial decline in".
"A profound decrease in slow-wave sleep had an immediate and significant adverse effect on insulin sensitivity and glucose tolerance".
By contrast, acute hypotensive anemia (saline hemodilution) resulted in a profound decrease in both brain and muscle tissue PtO2 and evidence of inadequate global perfusion (lactic acidosis).
Meter-scale variability in lake level since ca. AD 1930 is associated with precipitation sourced from the Western Indian Ocean with IOD variability, whereas the 15 m drop in water level in the early 20th century may reflect a profound decrease in moisture from Atlantic/Congo Basin source.
Journaling the triggers of your pain can be incredibly beneficial as well, since shifts in diet, sleep habits, or exposure to stress can lead to a profound decrease in pain.
Our data also demonstrated a profound decrease in IFNγsignaling in A20 overexpressing livers.
A profound decrease in β-agonist stimulated cAMP was found, which led to additional studies indicating a post-receptor phenomenon.
However, a change in the cut-offs from 3/8 to 4/8 criteria resulted in a profound decrease of cases in septic shock from 103 to 93 cases.
Prenatal endotoxin exposure in rabbits revealed similar results with a profound decrease of neurons in the anterior thalamus [ 8].
Interestingly, while the cross-reactive neutralization activities against VN04 H5 were completely abolished after the depletion of IgG, the neutralization activities against homologous TE09 H1 were only partially removed though a profound decrease was observed in 3 out of 4 patients (Table 2).
A recent study demonstrates that wild-type magA+ and trans-complemented magA organisms grow more rapidly and cause a more profound decrease in ERG a- and b-waves and cellular infiltration in a mouse model than the magA deficient organism [29].
DM patients with cardiac autonomic neuropathy who received general anaesthesia experienced a more profound decrease in HR and BP and an increased use of vasoactive drugs during induction [ 2].
