GEN1 is a monomer in solution and cleaves 5′ flaps and replication forks as a monomer but can form a dimer on Holliday junctions to ensure their productive resolution by symmetrical, bilateral cleavage (Rass et al., 2010).
A key characteristic of canonical HJRs is that they bind and process their substrate as dimers to achieve substrate recognition and productive resolution and predominantly form homodimers in solution in the absence of substrate (Lilley and White, 2001).
I try my best to satisfy the client's needs, and to achieve productive resolutions, using a combination of negotiation, as well as litigation strategies.
"The government knows where to find us if they want to have a productive conversation about resolutions that don't involve Edward Snowden behind bars," said the American Civil Liberties Union's Ben Wizner, the central figure on Snowden's legal team.
David Cantor, a spokesman for the city's Department of Education, said: "We're seeking a resolution that would address parents' concerns and had a productive meeting to that end today.
It should be kept in mind that, depending on the circumstances, "stonewalling" or "war" may not be a productive response; that, generally, an activist's ideas should be carefully evaluated; and that compromise ultimately may be the preferred resolution.
Fever, a productive cough with white sputum, and wheezing developed ≈3 weeks after his second infusion of tocilizumab, which resulted in RA symptom resolution.
At Missouri Veblen enjoyed a productive period.
"I had a productive trip.
"It was a productive meeting".
