Indeed, there is evidence that families misperceive the process of randomization as a mechanism for triaging patients when a therapy is too scarce to offer to everyone [ 2].
Reasons for attrition may differ for randomized trials, e.g. random assignment to an unwanted treatment group, and the process of randomization and the types of interventions, which, make it difficult to extrapolate the effectiveness of certain retention methods to cohort studies.
The process of randomization is conducted by a computer program by minimization based on the GP's practice size (single practice vs. group practice), the location of the practice within Hamburg classified into the two categories (central vs. peripheral) and income level of the practice's local district classified into three categories (low, middle and high).
Back in 2003, we published 'MAX' randomization, a process of non-degenerate saturation mutagenesis using exactly 20 codons (one for each amino acid) or else any required subset of those 20 codons.
In the subsequent process of randomization, three randomization techniques: RandA, RandB, and RandC are used to generate 300 candidate vectors where 100 vectors are generated for each (see also[2]).
Also Paul, instead of going through the annual process of randomization and tweaking, isn't it simpler if they created three or four "best-case" fixture lists and used these cyclically over three or four seasons (Of course, making adjustments only to accommodate promotions and relegations) ?
They were also unaware of the risks and benefits of treatment and the process of randomization.
However, this was unlikely in the included trials because of the process of randomization.
We inquired as to how participants felt towards the process of randomization.
Investigators sent randomizations requests by fax to the central randomization center (CRC) responsible for the process of randomization.
